The Cooler Master Cosmos S has a the E-ATX form factor. Extended ATX is a slightly deeper version of the ATX standard which is designed to provide all the advantages of ATX but with slightly more room. Using the E-ATX standard, the case can house motherboards and power supplies with form factors ATX and E-ATX. The dimensions of the case itself (LxWxH) are 628mm x 266mm x 598mm.

The Cooler Master Cosmos S has seven expansion slots, so there is plenty of room for extra components, which may be a deciding factor when planning on the longevity and build type of a PC system. The case has seven 5.25" drive bays, which is more than enough to house various drives, particularly optical drives. With four 3.5" drive bays there is also plenty of extra HDD space as well. Installing a solid-state drive on this case would require a 3.5" adapter. Installation of hard drives into these drive bays is made all the more easier by screwless rails that allow tool-less mounting.

Made primarily of Aluminium, the Cooler Master Cosmos S is built to be strong, lightweight, and well-ventilated. This often comes at a price premium, but some see the benefits to be completely worth it. Whatever your case's material, it is important to keep a consistent airflow so that heat doesn't build up inside. It is therefore advised that you make use of the available built-in case fans and fan installation sections.